Article
Phase II study of gemcitabine, oxaliplatin and capecitabine in patients with KRAS exon 2 mutated biliary tract cancers.
Acta oncologica (Stockholm, Sweden) - 1 Mar 2020
Jensen Lars H, Andersen Rikke Fredslund, Byriel Lene, Fernebro Eva, Jakobsen Anders, Lindebjerg Jan, Nottelmann Lise, Ploen John, Hansen Torben F
Abstract excerpt
Background: Molecular markers may identify subgroups of patients with clinically distinct behavior and response to treatment. In some gastrointestinal tumors, KRAS has prognostic value and negative predictive value. This is the first prospective study to report the outcome of combination chemotherapy in biliary tract cancer patients with KRAS mutation.Methods: From 2009 to 2015, 25 patients were included from two...
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