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Article

MicroRNA Dysregulation in Human Thyroid Cells Following Exposure to Ionizing Radiation

17 Feb 2011

Abstract excerpt

BACKGROUND: Ionizing radiation is a well-known mutagen and a risk factor for thyroid cancer. MicroRNAs (miRNAs) play an important role in the regulation of gene expression on post-transcriptional level and are dysregulated in thyroid cancer. The goal of this study was to investigate the effects of acute exposure to 1 and 10 Gy of γ-irradiation on miRNA expression in normal human thyroid cells. METHODS: Expression...

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PMID: 21323591
DOI: 10.1089/thy.2010.0376

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