Article
Association of common variants of vascular endothelial growth factor and interleukin-18 genes with allograft survival in renal transplant recipients of North India.
DNA and cell biology - 1 May 2011
Mittal Rama Devi, Srivastava Priyanka, Singh Vibha, Jaiswal Praveen, Kapoor Rakesh
Abstract excerpt
Increased vascular endothelial growth factor (VEGF) production promotes enhanced endothelial permeability, enhanced leukocyte migration into the allograft, thereby leading to a clinically recognized rejection episode. Interleukin-18 (IL-18), a potent proinflammatory cytokine, may also be involved in mechanisms of kidney allograft rejection. The present study was, therefore, undertaken to investigate the...
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