Article
Targeted eicosanoid lipidomics of exhaled breath condensate provide a distinct pattern in the aspirin-intolerant asthma phenotype.
The Journal of allergy and clinical immunology - 1 May 2011
Sanak Marek, Gielicz Anna, Bochenek Grażyna, Kaszuba Marek, Niżankowska-Mogilnicka Ewa, Szczeklik Andrew
Abstract excerpt
BACKGROUND: Eicosanoids, important signaling and inflammatory molecules, are present in exhaled breath condensate (EBC) in very low concentrations, requiring highly sensitive analytic methods for their quantification. OBJECTIVE: We sought to assess a vast platform of eicosanoids in different asthma phenotypes, including aspirin-intolerant asthma, by means of a recently developed analytic approach based on mass...
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