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Article

When a module is not a domain: the case of the REJ module and the redefinition of the architecture of polycystin-1.

The Biochemical journal - 1 May 2011

Schröder Samantha, Fraternali Franca, Quan Xueping, Scott David, Qian Feng, Pfuhl Mark

Abstract excerpt

The extracellular region of a group of cell-surface receptors known as the polycystic kidney disease 1 family, containing, among others, polycystin-1, has been controversially described as containing four FNIII (fibronectin type III) domains or one REJ (receptor of egg jelly protein) module in the same portion of polypeptide. Stimulated by recent atomic force microscopy work, we re-examined the similarity of...

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Identifiers

PMID: 21314639
DOI: 10.1042/BJ20101810
PMCID: PMC4979573

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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