Article
Investigating paraoxonase-1 gene Q192R and L55M polymorphism in patients with renal cell cancer.
Genetics and molecular research : GMR - 1 Feb 2011
Uyar O A, Kara M, Erol D, Ardicoglu A, Yuce H
Abstract excerpt
Increased oxidative stress can help promote carcinogenesis, including development of renal cell carcinoma. The enzyme protects low-density lipoproteins from oxidation and can be a factor in this process. PON1 Q192R and L55M paraoxonase gene polymorphisms were assessed in 60 renal cell carcinoma patients and 60 healthy controls. Genotypes were examined by PCR; the restriction enzyme AlwI was used to examine the...
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