Article
Environmental and genetic preconditioning for long-term anoxia responses requires AMPK in Caenorhabditis elegans.
PloS one - 3 Feb 2011
LaRue Bobby L, Padilla Pamela A
Abstract excerpt
BACKGROUND: Preconditioning environments or therapeutics, to suppress the cellular damage associated with severe oxygen deprivation, is of interest to our understanding of diseases associated with oxygen deprivation. Wildtype C. elegans exposed to anoxia enter into a state of suspended animation in which energy-requiring processes reversibly arrest. C. elegans at all developmental stages survive 24-hours of...
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