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Article

Advances in understanding the pathogenesis of familial thrombocythaemia.

British journal of haematology - 1 Mar 2011

Teofili Luciana, Larocca Luigi M

Abstract excerpt

Familial thrombocytosis can be divided into two broad categories. The first includes inherited syndromes that affect only the megakaryocytic lineage with Mendelian inheritance, high penetrance and polyclonal haematopoiesis. The second category includes inherited predisposition to true Philadelphia-negative myeloproliferative neoplasms (MPN) and is characterized by low penetrance, clonal haematopoiesis and...

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Source

Identifiers

PMID: 21303356
DOI: 10.1111/j.1365-2141.2010.08500.x

Genes

JAK2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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