Article
COMT Val158Met variant and functional haplotypes associated with childhood ADHD history in women with bulimia nervosa.
Progress in neuro-psychopharmacology & biological psychiatry - 1 Jun 2011
Yilmaz Zeynep, Kaplan Allan S, Zai Clement C, Levitan Robert D, Kennedy James L
Abstract excerpt
Up to one third of patients with bulimia nervosa (BN) report a history of ADHD symptoms, and both disorders may also be associated with dopaminergic abnormalities. COMT gene, coding for an enzyme responsible for the degradation of dopamine, may play a part in the etiology of ADHD and BN. This study aimed to (1) examine if certain variants of the COMT genetic markers (rs6269, rs4633, rs4818 and rs4680) are more...
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