Signal transduction of a tissue interaction during embryonic heart development.

doi:10.1091/mbc.1.3.301

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Signal transduction of a tissue interaction during embryonic heart development.

Cell regulation - 1 Feb 1990

Runyan R B, Potts J D, Sharma R V, Loeber C P, Chiang J J, Bhalla R C

Abstract excerpt

During early cardiac development, progenitors of the valves and septa of the heart are formed by an epithelial-mesenchymal cell transformation of endothelial cells of the atrioventricular (AV) canal. We have previously shown that this event is due to an interaction between the endothelium and products of the myocardium found within the extracellular matrix. The present study examines signal transduction...

Topics

1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine
Alkaloids
Animals
Calcium
Chick Embryo
Cholera Toxin
Endothelium
Enzyme Activation
Extracellular Matrix Proteins
Fetal Heart
GTP-Binding Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genistein

Isoflavones

Isoquinolines

Myocardium

Pertussis Toxin

Phenotype

Piperazines

Source

Open in PubMed Open full text

Identifiers

PMID: 2129222
DOI: 10.1091/mbc.1.3.301
PMCID: PMC361475

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2129222-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Signal transduction of a tissue interaction during embryonic heart development.PMID 2129222Read ↗

TGF‐β3‐Mediated tissue interaction during embryonic heart developmentSemantic proximity Read ↗

Cellular phenotype transformation during early embryogenesis: a role for focal adhesion kinase?Semantic proximity Read ↗

The constitutively active N111G-AT1 receptor for angiotensin II modifies the morphology and cytoskeletal organization of HEK-293 cells.Semantic proximity Read ↗

Selective restoration of calcium coupling to muscarinic M(3) receptors in contractile cultured airway myocytes.Semantic proximity Read ↗

Role of the prostanoid FP receptor in action potential generation and phenotypic transformation of NRK fibroblasts.Semantic proximity Read ↗

Cell-cell interaction in the heart via Wnt/ -catenin pathway after cardiac injurySemantic proximity Read ↗

Endothelial cell–cardiomyocyte crosstalk in heart development and diseaseSemantic proximity Read ↗

Cardiac fibroblasts and mechanosensation in heart development, health and diseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.