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Article

New and highly efficient methodology for screening high-yield strains of cytotoxic deacetylmycoepoxydiene (DAM).

Letters in applied microbiology - 1 May 2011

Zhang W, Wang M, Huang Y, Chea S K P, Zheng Z, Qian X, Shen Y

Abstract excerpt

AIMS: To establish a highly efficient methodology for screening high yield strains of cytotoxic deacetylmycoepoxydiene (DAM), to meet the need of research on its mechanism of anti-tumor properties and in vivo toxicity studies. METHODS AND RESULTS: A simple, sensitive, and highly repetitive screening procedure 'Antimicrobial-TLC-HPLC' (ATH) was established for the rapid obtaining of high-yielding DAM mutants to...

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PMID: 21284681
DOI: 10.1111/j.1472-765X.2011.03015.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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