Glycoprotein molecules in the walls of Schizosaccharomyces pombe wild-type cells and a morphologically altered mutant resistant to papulacandin B.

Abstract excerpt

Schizosaccharomyces pombe cell walls contain two major glycoprotein species, I and II, with molecular masses of 2 x 10(6) and 5 x 10(5) Da respectively, as determined by gel filtration chromatography and PAGE. The ratio of sugar to protein is higher in species I than in species II. Much of the sugar in both glycoproteins (about 85% in wild-type cells) is O-linked to the peptide moiety. The morphological sph1...

Topics

• Acetylglucosaminidase
• Aminoglycosides
• Anti-Bacterial Agents
• Antifungal Agents
• Carbohydrates
• Cell Wall
• Chromatography, Gel
• Culture Media
• Drug Resistance
• Glycoproteins
• Hydrolases