Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Phenotypic heterogeneity in mycobacterial stringent response.

BMC systems biology - 27 Jan 2011

Ghosh Sayantari, Sureka Kamakshi, Ghosh Bhaswar, Bose Indrani, Basu Joyoti, Kundu Manikuntala

Abstract excerpt

BACKGROUND: A common survival strategy of microorganisms subjected to stress involves the generation of phenotypic heterogeneity in the isogenic microbial population enabling a subset of the population to survive under stress. In a recent study, a mycobacterial population of M. smegmatis was shown to develop phenotypic heterogeneity under nutrient depletion. The observed heterogeneity is in the form of a bimodal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adaptation, Physiological
Share to Flow Cytometry
Share to Gene Expression Regulation, Bacterial

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Ligases

Share to Models, Biological

Share to Mycobacterium

Share to Sigma Factor

Share to Stress, Physiological

Source

Open in PubMed Open full text

Identifiers

PMID: 21272295
DOI: 10.1186/1752-0509-5-18
PMCID: PMC3045321

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Phenotypic heterogeneity in mycobacterial stringent response.PMID 21272295Read ↗

Types and functions of heterogeneity in mycobacteria.Semantic proximity Read ↗

Temporal tuning of switch-like virulence expression resolves environmental uncertainty through phenotypic heterogeneity.Semantic proximity Read ↗

Temporal tuning of switch-like virulence expression resolves environmental uncertainty through phenotypic heterogeneitySemantic proximity Read ↗

Bistable expression of virulence genes in salmonella leads to the formation of an antibiotic-tolerant subpopulation.Semantic proximity Read ↗

Phenotypic switching in gene regulatory networks.Semantic proximity Read ↗

The importance of being persistent: heterogeneity of bacterial populations under antibiotic stress.Semantic proximity Read ↗

Chaperone-mediated stress-sensing in <i>Mycobacterium tuberculosis</i> enables fast activation and sustained responseSemantic proximity Read ↗

Deletion of a mycobacterial divisome factor collapses single-cell phenotypic heterogeneity.Semantic proximity Read ↗

Defining heterogeneity within bacterial populations via single cell approaches.Semantic proximity Read ↗

Single-Cell Analysis of Mycobacteria Using Microfluidics and Time-Lapse Microscopy.Semantic proximity Read ↗

Subpopulations of sensorless bacteria drive fitness in fluctuating environments.Semantic proximity Read ↗

Noise-Driven Phenotypic Heterogeneity with Finite Correlation Time in Clonal Populations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.