Article
Clinical significance of osteoprotegerin expression in human colorectal cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Apr 2011
Tsukamoto Shunsuke, Ishikawa Toshiaki, Iida Satoru, Ishiguro Megumi, Mogushi Kaoru, Mizushima Hiroshi, Uetake Hiroyuki, Tanaka Hiroshi, Sugihara Kenichi
Abstract excerpt
PURPOSE: This study aimed to identify a novel biomarker or a target of treatment for colorectal cancer (CRC). EXPERIMENTAL DESIGN: The expression profiles of cancer cells in 104 patients with CRC were examined using laser microdissection and oligonucleotide microarray analysis. Overexpression in CRC cells, especially in patients with distant metastases, was a prerequisite to select candidate genes. The mRNA...
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