Article
Single-nucleotide polymorphisms in the KCNN3 gene associate with preterm birth.
Reproductive sciences (Thousand Oaks, Calif.) - 1 Mar 2011
Day Lori J, Schaa Kendra L, Ryckman Kelli K, Cooper Meg, Dagle John M, Fong Chin-To, Simhan Hyagriv N, Merrill David C, Marazita Mary L, Murray Jeffrey C, England Sarah K
Abstract excerpt
The objectives were to determine whether single-nucleotide polymorphisms (SNPs) in KCNN3 (encodes the small conductance calcium-activated potassium channel subfamily N, member 3), associate with preterm birth (PTB). In all, 602 preterm families with at least 1 preterm (<37 weeks gestation) infant were studied: DNA from the infant and one or both parents were genotyped for 16 SNPs in KCNN3. A region of interest...
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