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Article

Replicative phenotyping adds value to genotypic resistance testing in heavily pre-treated HIV-infected individuals--the Swiss HIV Cohort Study.

Journal of translational medicine - 21 Jan 2011

Fehr Jan, Glass Tracy R, Louvel Séverine, Hamy François, Hirsch Hans H, von Wyl Viktor, Böni Jürg, Yerly Sabine, Bürgisser Philippe, Cavassini Matthias, Fux Christoph A, Hirschel Bernard, Vernazza Pietro, Martinetti Gladys, Bernasconi Enos, Günthard Huldrych F, Battegay Manuel, Bucher Heiner C, Klimkait Thomas

Abstract excerpt

BACKGROUND: Replicative phenotypic HIV resistance testing (rPRT) uses recombinant infectious virus to measure viral replication in the presence of antiretroviral drugs. Due to its high sensitivity of detection of viral minorities and its dissecting power for complex viral resistance patterns and mixed virus populations rPRT might help to improve HIV resistance diagnostics, particularly for patients with multiple...

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Share to Anti-HIV Agents
Share to Dose-Response Relationship, Drug

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Resistance, Viral

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Source

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Identifiers

PMID: 21255386
DOI: 10.1186/1479-5876-9-14
PMCID: PMC3032678

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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