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Article

Development of an ovarian cancer screening decision model that incorporates disease heterogeneity: implications for potential mortality reduction.

Cancer - 1 Feb 2011

Havrilesky Laura J, Sanders Gillian D, Kulasingam Shalini, Chino Junzo P, Berchuck Andrew, Marks Jeffrey R, Myers Evan R

Abstract excerpt

BACKGROUND: Pathologic and genetic data suggest that epithelial ovarian cancer may consist of indolent and aggressive phenotypes. The objective of the current study was to estimate the impact of a 2-phenotype paradigm of epithelial ovarian cancer on the mortality reduction achievable using available screening technologies. METHODS: The authors modified a Markov model of ovarian cancer natural history (the...

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PMID: 21254049
DOI: 10.1002/cncr.25624

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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