Article
Molecular mechanisms of epidermal growth factor receptor overexpression in patients with cervical cancer.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 May 2011
Schrevel Marlies, Gorter Arko, Kolkman-Uljee Sandra M, Trimbos J Baptist M Z, Fleuren Gert Jan, Jordanova Ekaterina S
Abstract excerpt
The epidermal growth factor receptor is overexpressed in 70-90% of cervical cancers. Previously, we have shown that epidermal growth factor receptor overexpression independently predicts poor prognosis in cervical cancer patients, which makes it a potential therapeutic target. The aim of this study was to systematically analyze the molecular mechanism leading to epidermal growth factor receptor overexpression in...
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