Article
Treatment effects and predictors of a 24-week course of interferon alpha-2b plus ribavirin combination therapy for patients with chronic hepatitis C.
Journal of gastroenterology and hepatology - 1 Jul 2006
Tomimatsu Masahiko, Aizawa Yoshio, Chuganji Yoshimichi, Ishizuka Hideo, Fujita Yoshiyuki, Aizawa Ryouichi, Abe Hiroshi, Matsuda Takako, Itou Yumi, Nakanishi Hiroyuki, Ushiyama Hisashi, Higuchi Teruhisa, Fujimoto Tomoko, Endou Hitoshi, Iga Daijiro, Ohta Kazuki, Kuroda Hiroyuki
Abstract excerpt
BACKGROUND AND AIMS: In chronic hepatitis C patients with genotype 1b and a high viral load, the sustained virological response (SVR) rate remained as low as 2-3% with conventional interferon (IFN) monotherapy, but improved to more than 20% with IFN alpha-2b plus ribavirin combination therapy. This study examined the therapeutic effects and predictors of this combination therapy. METHODS: Subjects were 105...
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