Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Extraribosomal functions associated with the C terminus of the 37/67 kDa laminin receptor are required for maintaining cell viability.

Cell death & disease - 1 Jan 2010

Scheiman J, Jamieson K V, Ziello J, Tseng J-C, Meruelo D

Abstract excerpt

The 37/67 kDa laminin receptor (LAMR) is a multifunctional protein, acting as an extracellular receptor, localizing to the nucleus, and playing roles in rRNA processing and ribosome assembly. LAMR is important for cell viability; however, it is unclear which of its functions are essential. We developed a silent mutant LAMR construct, resistant to siRNA, to rescue the phenotypic effects of knocking down endogenous...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acids
Share to G1 Phase
Share to Gene Knockdown Techniques

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Molecular Weight

Share to Protein Transport

Share to Ribosomal Proteins

Share to Ribosomes

Share to RNA, Small Interfering

Source

Open in PubMed Open full text

Identifiers

PMID: 21243100
DOI: 10.1038/cddis.2010.19
PMCID: PMC3019570

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Extraribosomal functions associated with the C terminus of the 37/67 kDa laminin receptor are required for maintaining cell viability.PMID 21243100Read ↗

Looking into laminin receptor: critical discussion regarding the non‐integrin 37/67‐<scp>kDa</scp>laminin receptor/<scp>RPSA</scp>proteinSemantic proximity Read ↗

Interactions between PrPc and other ligands with the 37-kDa/67-kDa laminin receptorSemantic proximity Read ↗

The 67-kDa laminin receptor originated from a ribosomal protein that acquired a dual function during evolutionSemantic proximity Read ↗

LRP/LR as an alternative promising target in therapy of prion diseases, Alzheimer's disease and cancer.Semantic proximity Read ↗

Cloning and characterization of full-length coding sequence (CDS) of the ovine 37/67-kDa laminin receptor (RPSA).Semantic proximity Read ↗

Emerging roles of the cellular prion protein (PrPC) and 37/67 kDa laminin receptor (RPSA) interaction in cancer biologySemantic proximity Read ↗

A trans-dominant negative 37kDa/67kDa laminin receptor mutant impairs PrP(Sc) propagation in scrapie-infected neuronal cells.Semantic proximity Read ↗

New insights into the metastasis-associated 67 kD laminin receptorSemantic proximity Read ↗

Scrapie-infected transgenic mice expressing a laminin receptor decoy mutant reveal a prolonged incubation time associated with low levels of PrPres.Semantic proximity Read ↗

Yeast Proteins Related to the p40/Laminin Receptor Precursor Are Essential Components of the 40 S Ribosomal SubunitSemantic proximity Read ↗

Mapping the essential structures of human ribosomal protein L7 for nuclear entry, ribosome assembly and function.Semantic proximity Read ↗

Structural and functional properties of ribosomal protein L7 from humans and rodentsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.