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Article

Increased zona pellucida thickness and meiotic spindle disruption in oocytes from cigarette smoking mice

12 Jan 2011

Abstract excerpt

BACKGROUND The precise effects of cigarette smoking on female fertility have not yet been clearly defined. We have used a mouse model that mimics human smoking and is able to control for variables that may confound clinical studies to assess the impact of chronic smoking on the quality of mouse oocytes. METHODS Mice received cigarette smoke directly to their lungs for 12 weeks. Lung tissue was analyzed for...

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PMID: 21233109
DOI: 10.1093/humrep/deq393

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