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Article

Fatty acid transport in multiple carboxylase deficiency fibroblasts.

Journal of inherited metabolic disease - 1 Jan 1990

Packman S, Whitney S

Abstract excerpt

Holocarboxylase synthetase (HS) and biotinidase deficiencies have been identified as causes of biotin-responsive multiple carboxylase deficiency. Acetyl-CoA carboxylase (ACC) deficiency has been shown to occur in multiple carboxylase deficiency, and HS(-) fibroblasts are being employed to investigate compensatory regulatory responses in cells deficient in ACC. In previous studies, biotin starved HS(-) fibroblasts...

Topics

Arachidonic Acid
Arachidonic Acids
Biological Transport, Active
Biotin
Carboxy-Lyases
Cell Line
Culture Media
Fatty Acids
Fibroblasts
Humans
Mutation
Oleic Acid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Oleic Acids

Palmitic Acid

Palmitic Acids

Source

Identifiers

PMID: 2123277
DOI: 10.1007/BF01799574

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2123277-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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