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Article

Generation of capsule-deficient Neisseria meningitidis strains by homologous recombination.

Molecular microbiology - 1 Jul 1990

Frosch M, Schultz E, Glenn-Calvo E, Meyer T F

Abstract excerpt

Capsule-deficient mutants of Neisseria meningitidis serogroup B strain B1940 were constructed by allelic replacement using the plasmids pMF120 and pMF121, which contain the flanking regions of the gene locus for the biosynthesis pathway of the group B meningococcal capsular polysaccharide. Southe...

Topics

Alleles
Blotting, Southern
Cloning, Molecular
DNA, Bacterial
Neisseria meningitidis
Plasmids
Polysaccharides, Bacterial
Recombination, Genetic
Restriction Mapping
Serotyping
Transformation, Bacterial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 2122175
DOI: 10.1111/j.1365-2958.1990.tb00697.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2122175-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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