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Article

Screening of OPTN in French familial amyotrophic lateral sclerosis.

Neurobiology of aging - 1 Mar 2011

Millecamps Stéphanie, Boillée Séverine, Chabrol Elodie, Camu William, Cazeneuve Cécile, Salachas François, Pradat Pierre-François, Danel-Brunaud Véronique, Vandenberghe Nadia, Corcia Philippe, Le Forestier Nadine, Lacomblez Lucette, Bruneteau Gaëlle, Seilhean Danielle, Brice Alexis, Feingold Josué, Meininger Vincent, LeGuern Eric

Abstract excerpt

Mutations in OPTN gene encoding optineurin have recently been identified at the homozygote and heterozygote state in Japanese families with slowly progressive amyotrophic lateral sclerosis (ALS). OPTN had previously been involved in adult primary open angle glaucoma (POAG). We sequenced the codin...

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Source

Identifiers

PMID: 21220178
DOI: 10.1016/j.neurobiolaging.2010.11.005

Genes

OPTN

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21220178-2026-09-04.1. Manifest publication-graph-cohort-2026-09-04.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Screening of OPTN in French familial amyotrophic lateral sclerosis.PMID 21220178Read ↗

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