Article
The free and bound forms of Lpp occupy distinct subcellular locations in Escherichia coli.
Molecular microbiology - 1 Mar 2011
Cowles Charles E, Li Yongfeng, Semmelhack Martin F, Cristea Ileana M, Silhavy Thomas J
Abstract excerpt
The lipoprotein Lpp is the most numerically abundant protein in Escherichia coli, has been investigated for over 40 years, and has served as the paradigmatic bacterial lipoprotein since its initial discovery. It exists in two distinct forms: a 'bound-form', which is covalently bound to the cell's peptidoglycan layer, and a 'free-form', which is not. Although it is known that the carboxyl-terminus of bound-form...
Topics
- Bacterial Outer Membrane Proteins
- Escherichia coli
- Escherichia coli Proteins
- Intracellular Space
- Lipoproteins
- Mutation
- Protein Binding
- Staining and Labeling