Article
Cyclic GMP controls Rhodospirillum centenum cyst development.
Molecular microbiology - 1 Feb 2011
Marden Jeremiah N, Dong Qian, Roychowdhury Sugata, Berleman James E, Bauer Carl E
Abstract excerpt
Adenylyl cyclases are widely distributed across all kingdoms whereas guanylyl cyclases are generally thought to be restricted to eukaryotes. Here we report that the α-proteobacterium Rhodospirillum centenum secretes cGMP when developing cysts and that a guanylyl cyclase deletion strain fails to synthesize cGMP and is defective in cyst formation. The R. centenum cyclase was purified and shown to effectively...
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