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Article

HIF1A Is Essential for the Development of the Intermediate Plexus of the Retinal Vasculature

6 Jan 2011

Abstract excerpt

PURPOSE: HIF1A is one of the major transcription factors that regulate tissue response to low oxygen tension. It controls expression of a large number of genes involved in cell survival, proliferation, angiogenesis, and other cellular processes. HIF1A is present at increased levels in the early postnatal retina. In this study its potential function during postnatal development of the mouse retina and retinal...

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PMID: 21212189
DOI: 10.1167/iovs.10-6222

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