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Prospects of Induced Pluripotent Stem Cell Technology in Regenerative Medicine

7 Jan 2011

Abstract excerpt

Induced pluripotent stem (iPS) cells are derived from adult somatic cells via reprogramming with ectopic expression of four transcription factors (Oct3/4, Sox2, c-Myc and Klf4; or, Oct3/4, Sox2, Nanog, and Lin28), by which the resultant cells regain pluripotency, namely, the capability exclusively possessed by some embryonic cells to differentiate into any cell lineage under proper conditions. Given the ease in...

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PMID: 21210760
DOI: 10.1089/ten.teb.2010.0549

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