Article
Budding Capability of the Influenza Virus Neuraminidase Can Be Modulated by Tetherin
6 Jan 2011
Abstract excerpt
We have determined that, in addition to its receptor-destroying activity, the influenza virus neuraminidase is capable of efficiently forming virus-like particles (VLPs) when expressed individually from plasmid DNA. This observation applies to both human subtypes of neuraminidase, N1 and N2. However, it is not found with every strain of influenza virus. Through gain-of-function and loss-of-function analyses, a...
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