Article
Arabidopsis MKS1 is involved in basal immunity and requires an intact N-terminal domain for proper function.
PloS one - 28 Dec 2010
Petersen Klaus, Qiu Jin-Long, Lütje Juri, Fiil Berthe Katrine, Hansen Sidsel, Mundy John, Petersen Morten
Abstract excerpt
BACKGROUND: Innate immune signaling pathways in animals and plants are regulated by mitogen-activated protein kinase (MAPK) cascades. MAP kinase 4 (MPK4) functions downstream of innate immune receptors via a nuclear substrate MKS1 to regulate the activity of the WRKY33 transcription factor, which in turn controls the production of anti-microbial phytoalexins. METHODOLOGY/PRINCIPAL FINDINGS: We investigate the...
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