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Article

Mitochondrial pathogenic mutations are population-specific.

Biology direct - 31 Dec 2010

Breen Michael S, Kondrashov Fyodor A

Abstract excerpt

BACKGROUND: Surveying deleterious variation in human populations is crucial for our understanding, diagnosis and potential treatment of human genetic pathologies. A number of recent genome-wide analyses focused on the prevalence of segregating deleterious alleles in the nuclear genome. However, such studies have not been conducted for the mitochondrial genome. RESULTS: We present a systematic survey of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21194457
DOI: 10.1186/1745-6150-5-68
PMCID: PMC3022564

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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