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Article

Endurance, refuge, and reemergence of dengue virus type 2, Puerto Rico, 1986-2007.

Emerging infectious diseases - 1 Jan 2011

McElroy Kate L, Santiago Gilberto A, Lennon Niall J, Birren Bruce W, Henn Matthew R, Muñoz-Jordán Jorge L

Abstract excerpt

To study the evolution of dengue virus (DENV) serotype 2 in Puerto Rico, we examined the genetic composition and diversity of 160 DENV-2 genomes obtained through 22 consecutive years of sampling. A clade replacement took place in 1994-1997 during a period of high incidence of autochthonous DENV-2 and frequent, short-lived reintroductions of foreign DENV-2. This unique clade replacement was complete just before...

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Identifiers

PMID: 21192856
DOI: 10.3201/eid1701.100961
PMCID: PMC3204641

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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