Article
Noninvasive detection and imaging of molecular markers in live cardiomyocytes derived from human embryonic stem cells.
Biophysical journal - 5 Jan 2011
Pascut Flavius C, Goh Huey T, Welch Nathan, Buttery Lee D, Denning Chris, Notingher Ioan
Abstract excerpt
Raman microspectroscopy (RMS) was used to detect and image molecular markers specific to cardiomyocytes (CMs) derived from human embryonic stem cells (hESCs). This technique is noninvasive and thus can be used to discriminate individual live CMs within highly heterogeneous cell populations. Principal component analysis (PCA) of the Raman spectra was used to build a classification model for identification of...
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