[Tyrosine kinases in etiopathogenesis and therapy of malignant diseases--C-kit activating mutations].

Abstract excerpt

INTRODUCTION: In the last 15 years, the introduction of molecular biology methods and techniques for identifying mutations and measuring gene expression levels of mutated genes since recently, have enabled precise molecular diagnostics, classification and assessment of prognosis and therapeutic response of malignant disease to specific therapies. The increased knowledge of the cancer genome and the introduction...

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