Article
Non-coding RNAs: could they be the answer?
Briefings in functional genomics - 1 Sept 2011
Costa Fabricio F
Abstract excerpt
Despite a considerable amount of effort by different groups to evaluate the genetic traits associated with complex diseases by genome-wide association studies (GWAS), just a few regions, mainly linked to protein-coding genes, were identified. Recently, studies from different groups have implicated new classes of long non-coding RNAs (ncRNAs) to important molecular mechanisms. Additionally, high-throughput...
Topics
- Genome-Wide Association Study
- Humans
- Phenotype
- RNA, Untranslated
- Transcription, Genetic
