Article
Noncoding RNA transcription beyond annotated genes.
Current opinion in genetics & development - 1 Apr 2007
Carninci Piero, Hayashizaki Yoshihide
Abstract excerpt
Recent analyses based on high-throughput transcriptome data have revealed that the fraction of the genome that is transcribed largely exceeds the fraction encoding protein. Transcription of unconventional genes into noncoding RNAs is widespread and, in mammals, these RNAs comprise at least half the total number of RNAs transcribed by RNA polymerase II. Although the function of the majority of noncoding RNAs has...
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