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Article

DFNB89, a novel autosomal recessive nonsyndromic hearing impairment locus on chromosome 16q21-q23.2.

Human genetics - 1 Apr 2011

Basit Sulman, Lee Kwanghyuk, Habib Rabia, Chen Leon, Umm-e-Kalsoom, Santos-Cortez Regie Lyn P, Azeem Zahid, Andrade Paula, Ansar Muhammad, Ahmad Wasim, Leal Suzanne M

Abstract excerpt

DFNB89 is a novel autosomal recessive nonsyndromic hearing impairment (ARNSHI) locus that was mapped to 16q21-q23.2. Linkage to the region was established by carrying out genome-wide linkage scans in two unrelated, consanguineous Pakistani families segregating ARNSHI. The maximum multipoint LOD score is 9.7 for both families and for each family, a significant maximum LOD score of 6.0 and 3.7 were obtained. The...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21181198
DOI: 10.1007/s00439-010-0934-0
PMCID: PMC3312604

Genes

CALB2
CDH1
CDH11
CDH3
HAS3
NOB1
PLEKHG4
SMPD3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Research trail→

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DFNB89, a novel autosomal recessive nonsyndromic hearing impairment locus on chromosome 16q21-q23.2.PMID 21181198Read ↗

DFNB68, a novel autosomal recessive non-syndromic hearing impairment locus at chromosomal region 19p13.2.Semantic proximity Read ↗

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Autosomal recessive non-syndromic hearing loss genes in Pakistan during the previous three decades.Semantic proximity Read ↗

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Fine mapping of autosomal dominant nonsyndromic hearing impairment DFNA21 to chromosome 6p24.1-22.3.Semantic proximity Read ↗

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A gene for autosomal dominant hearing impairment (DFNA14) maps to a region on chromosome 4p16.3 that does not overlap the DFNA6 locus.Semantic proximity Read ↗

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