Article
Fine mapping of autosomal dominant nonsyndromic hearing impairment DFNA21 to chromosome 6p24.1-22.3.
American journal of medical genetics. Part A - 15 Aug 2005
de Brouwer Arjan P M, Kunst Hendrikus P M, Krebsova Alice, van Asseldonk Karin, Reis André, Snoeckx Rik L, Van Camp Guy, Cremers Cor W R J, Cremers Frans P M, Kremer Hannie
Abstract excerpt
Previously, the DFNA21 locus was positioned telomeric to the DFNA13 locus based on testing of candidate loci. One family member in this region did not carry the at risk haplotype, although he had the same nonspecific midfrequency hearing impairment as other affected family members. Hence, we performed a whole genome linkage scan excluding other regions of the genome and confirming the localization of DFNA21 to...
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