Article
Molecular Characterization and Variation of the Celiac Disease Epitope Domains among α-Gliadin Genes in Aegilops tauschii.
Journal of agricultural and food chemistry - 26 Apr 2017
Li Yu-Ge, Liang Hui-Hui, Bai Sheng-Long, Zhou Yun, Sun Guiling, Su Ya-Rui, Gao An-Li, Zhang Da-Le, Li Suo-Ping
Abstract excerpt
To explore the distribution and quantity of toxic epitopes in α-gliadins from Aegilops tauschii, a total of 133 complete α-gliadin coding sequences were obtained, including 69 pseudogenes with at least one premature stop codon and 64 genes with complete open reading frames (ORFs). Plenty of deletions and single amino acid substitutions were found in the 4 celiac disease (CD) toxic epitope domains through multiple...
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