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MicroRNAs involved in neoplastic transformation of liver cancer stem cells

1 Dec 2010

Abstract excerpt

BACKGROUND: The existence of cancer stem cells in hepatocellular carcinoma (HCC) has been verified by characterizing side population (SP) cells based on efflux of Hoechst 33342 dye from stem cells. Recent advances in microRNA (miRNA) biology have revealed that miRNAs play an important role in embryonic development and tumorigenesis. However, it is still unclear which miRNAs participate in the neoplastic...

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PMID: 21176238
DOI: 10.1186/1756-9966-29-169

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