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Article

Adriamycin nephropathy: a model of focal segmental glomerulosclerosis.

Nephrology (Carlton, Vic.) - 1 Jan 2011

Lee Vincent W S, Harris David C H

Abstract excerpt

Adriamycin nephropathy (AN) is a rodent model of chronic kidney disease that has been studied extensively and has enabled a greater understanding of the processes underlying the progression of chronic proteinuric renal disease. AN is characterized by podocyte injury followed by glomerulosclerosis, tubulointerstitial inflammation and fibrosis. Genetic studies have demonstrated a number of loci that alter both risk...

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Identifiers

PMID: 21175974
DOI: 10.1111/j.1440-1797.2010.01383.x

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