Article
Effective population size and the efficacy of selection on the X chromosomes of two closely related Drosophila species.
Genome biology and evolution - 1 Jan 2011
Andolfatto Peter, Wong Karen M, Bachtrog Doris
Abstract excerpt
The prevalence of natural selection relative to genetic drift is of central interest in evolutionary biology. Depending on the distribution of fitness effects of new mutations, the importance of these evolutionary forces may differ in species with different effective population sizes. Here, we survey population genetic variation at 105 orthologous X-linked protein coding regions in Drosophila melanogaster and its...
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