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Article

Cataract-associated mutant E107A of human gammaD-crystallin shows increased attraction to alpha-crystallin and enhanced light scattering.

Proceedings of the National Academy of Sciences of the United States of America - 11 Jan 2011

Banerjee Priya R, Pande Ajay, Patrosz Julita, Thurston George M, Pande Jayanti

Abstract excerpt

Several point mutations in human γD-crystallin (HGD) are now known to be associated with cataract. So far, the in vitro studies of individual mutants of HGD alone have been sufficient in providing plausible molecular mechanisms for the associated cataract in vivo. Nearly all the mutant proteins i...

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Identifiers

PMID: 21173272
DOI: 10.1073/pnas.1014653107
PMCID: PMC3021023

Genes

HGD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21173272-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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