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Article

Rab27a Is Required for Human Cytomegalovirus Assembly

8 Dec 2010

Abstract excerpt

Human cytomegalovirus (HCMV) completes its final envelopment on intracellular membranes before it is released from the cell. The mechanisms underlying these processes are not understood. Here we studied the role of Rab27a, a regulator of lysosome-related organelle transport, in HCMV production. HCMV infection increased Rab27a expression, and recruitment of Rab27a to membranous strutures at the assembly site....

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PMID: 21170347
DOI: 10.1371/journal.pone.0015318

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