Article
Capsaicin induction of esophageal symptoms in different phenotypes of gastroesophageal reflux disease.
Revista de gastroenterologia de Mexico - 1 Jan 2000
Herrera-López J A, Mejía-Rivas M A, Vargas-Vorackova F, Valdovinos-Díaz M A
Abstract excerpt
BACKGROUND: Type 1 vanilloid receptors (TRPV1) have been described on esophageal afferent sensitive neurons. Stimulation of TRPV1 receptors with capsaicin may induce heartburn. Capsaicin is the pungent component of chili and the most extensively studied TRPV1 agonist. OBJECTIVES: To investigate the effect of esophageal stimulation with intraesophageal capsaicin administration on induction of esophageal symptoms...
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