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Article

Triple negative breast cancer: unmet medical needs.

Breast cancer research and treatment - 1 Feb 2011

Pal Sumanta Kumar, Childs Barrett H, Pegram Mark

Abstract excerpt

Triple negative breast cancer (TNBC) is an aggressive clinical phenotype characterized by lack of expression (or minimal expression) of estrogen receptor (ER) and progesterone receptor (PR) as well as an absence of human epidermal growth factor receptor-2 (HER2) overexpression. It shows substantial overlap with basal-type and BRCA1-related breast cancers, both of which also have aggressive clinical courses....

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Source

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Identifiers

PMID: 21161370
DOI: 10.1007/s10549-010-1293-1
PMCID: PMC3244802

Genes

BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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