Alignment-free estimation of nucleotide diversity.

Abstract excerpt

MOTIVATION: Sequencing capacity is currently growing more rapidly than CPU speed, leading to an analysis bottleneck in many genome projects. Alignment-free sequence analysis methods tend to be more efficient than their alignment-based counterparts. They may, therefore, be important in the long run for keeping sequence analysis abreast with sequencing. RESULTS: We derive and implement an alignment-free estimator...

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