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Article

Racial differences in MLH1 and MSH2 mutation: an analysis of yellow race and white race based on the InSiGHT database.

Journal of bioinformatics and computational biology - 1 Dec 2010

Wei Wenqian, Liu Lei, Chen Jian, Jin Ke, Jiang Fan, Liu Fangqi, Fan Rong, Cheng Zhe, Shen Meng, Xue Chenyi, Cai Sanjun, Xu Ye, Nan Peng

Abstract excerpt

MLH1 and MSH2 mutations underlie 90% of hereditary nonpolyposis colorectal cancer (HNPCC) mutations. The International Society of Gastrointestinal Hereditary Tumors (InSiGHT) has established an international database of mutations associated with HNPCC. Based on the InSiGHT database and the original references that reported the mutations, we analyzed the distributions of MLH1 and MSH2 mutations in yellow race and...

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Share to Adaptor Proteins, Signal Transducing
Share to Colorectal Neoplasms, Hereditary Nonpolyposis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to MutL Protein Homolog 1

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Source

Identifiers

PMID: 21155023
DOI: 10.1142/s0219720010005154

Genes

MLH1
MSH2

Variants

Provenance

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