Article
Arabidopsis BRCA2 and RAD51 proteins are specifically involved in defense gene transcription during plant immune responses.
Proceedings of the National Academy of Sciences of the United States of America - 28 Dec 2010
Wang Shui, Durrant Wendy E, Song Junqi, Spivey Natalie W, Dong Xinnian
Abstract excerpt
Systemic acquired resistance (SAR) is a plant immune response associated with both transcriptional reprogramming and increased homologous DNA recombination (HR). SNI1 is a negative regulator of SAR and HR, as indicated by the increased basal expression of defense genes and HR in sni1. We found that the sni1 phenotypes are rescued by mutations in BREAST CANCER 2 (BRCA2). In humans, BRCA2 is a mediator of RAD51 in...
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