Article
Influence of CYP2C9 and VKORC1 polymorphisms on warfarin and acenocoumarol in a sample of Lebanese people.
Journal of clinical pharmacology - 1 Oct 2011
Esmerian Maria O, Mitri Zahi, Habbal Mohammad-Zuheir, Geryess Eddy, Zaatari Ghazi, Alam Samir, Skouri Hadi N, Mahfouz Rami A, Taher Ali, Zgheib Nathalie K
Abstract excerpt
The authors assessed the impact of CYP2C9*2, CYP2C9*3, and/or VKORC1-1639G>A/1173C>T single-nucleotide polymorphisms on oral anticoagulants in a Lebanese population. This study recruited 231 Lebanese participants on long-term warfarin or acenocoumarol maintenance therapy with an international normalized ratio (INR) monitored at the American University of Beirut Medical Center. CYP2C9 and VKORC1 variant alleles...
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